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Small Molecule Inhibitors Cabozantinib (XL184) anti cancer drugs CAS 849217-68-1

Small Molecule Inhibitors Cabozantinib (XL184) anti cancer drugs CAS 849217-68-1

    • Small Molecule Inhibitors Cabozantinib (XL184) anti cancer drugs CAS 849217-68-1
    • Small Molecule Inhibitors Cabozantinib (XL184) anti cancer drugs CAS 849217-68-1
  • Small Molecule Inhibitors Cabozantinib (XL184) anti cancer drugs CAS 849217-68-1

    Thông tin chi tiết sản phẩm:

    Place of Origin: China
    Hàng hiệu: Sendi
    Chứng nhận: SGS,ISO9001
    Model Number: XL184

    Thanh toán:

    Minimum Order Quantity: 10 Grams
    Giá bán: 1.5 usd dollars per gram
    Packaging Details: Discreet and safe foil bag
    Delivery Time: Within 12hours after payment
    Payment Terms: West Union, T/T, Money Gram.,Bitcorn and bank transfer, D/P
    Supply Ability: 10000 Kg
    Liên hệ với bây giờ
    Chi tiết sản phẩm
    Name: Cabozantinib CAS: 849217-68-1
    MF: C28H24FN3O5 Description: White to off-white powder
    Functions: Anticancer small molecule inhibitors Assay: 99.00%
    Category: Pharmaceutical Grade MW: 502

    Anticancer small molecule inhibitors Cabozantinib (XL184) CAS 849217-68-1

     

    Quick details:

     

    Product Name Cabozantinib
    Synonyms

    N-(4-(6,7-dimethoxyquinolin-4-yloxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide;Cabozantinib;N-[4-[(6,7-Dimethoxy-4-quinolinyl)oxy]phenyl]-N'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide;XL184;Cabozantinib(XL184);XL-184 free base (Cabozantinib);BMS907351;N-(4-((6,7-DiMethoxyquino.

    Molecular Formula C28H24FN3O5
    Molecular Weight 502
    CAS Registry Number 849217-68-1
    Appearance White to off-white powder
    Loss on drying Not more than0.5%
    Chemical name Cabozantinib; XL184; N-[4-[(6,7-Dimethoxy-4-quinolinyl)oxy]phenyl]-N'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide

     

    What cabozantinib is ?


    Cabozantinib is a treatment for a rare type of thyroid cancer called medullary thyroid cancer. It is for people who can’t have surgery or whose cancer has spread to another part of the body.

    You may have cabozantinib as part of clinical trials for other types of cancer.

    Cabozantinib is also called by its brand name Cometriq.

     

    Cabozantinib  Description

     

    Cabozantinib (marketed under the tradename Cometriq, formerly known as XL184) is a potent VEGFR2 inhibitor with IC50 of 0.035 nM. XL-184 also displays potent activity against Met, Ret, Kit, FLT1, FLT3, FLT4, Tie2, and AXL. XL184 at low concentration(0.1-0.5 μM) is sufficient to induce marked inhibition of constitutive and inducible Met phosphorylation and its resultant downstream signaling in MPNST cells, and inhibit HGF-induced MPNST cell migration and invasion.

     

    How cabozantinib works


    Cabozantinib is a cancer growth blocker. It works by blocking particular proteins called protein kinases on cancer cells. The protein kinases encourage the cancer to grow. Cabozantinib blocks a number of these proteins and is called a multi kinase inhibitor. It also stops the cancer cells growing blood vessels, which the cells need to be able to grow.

    Cabozantinib may shrink the cancer or stop it growing for a time.

     

    Cabozantinib COA

     

    Items Specifications Results
    Appearance White to whitish crystal powder Conforms
    Loss on drying NMT 0.5% 0.33%
    Residue on ignition NMT 0.1% Conforms
    Heavy metal NMT 20ppm Conforms
    Assay (HPLC) NLT 99.5% 99.77%
    Related substances NMT 0.5% 0.23%
    Single impurity NMT 0.1% 0.07%
    Conclusion: Complies to the Enterprise standard

     

    How you have cabozantinib ?


    Cabozantinib comes as capsules. You take them once a day. Swallow them whole and don’t open them. The capsules come in different colours – orange and grey. How many you take depends on your needs. Your doctor may change the dose during the treatment.

     

    You should take the capsules at the same time each day. Don’t eat for at least 2 hours before you take them and for an hour after taking them.

     

    If you forgot to take a dose and it is more than 12 hours until your next dose then take the missed dose and the next dose as normal.

     

    If you forgot to take a dose and it is less than 12 hours until your next dose then miss that dose and take your next dose as normal.

     

    It is very important that you take the tablets according to the instructions your doctor or pharmacist gives you. For example, whether you have a full or empty stomach can affect how much of a drug gets into your bloodstream. So check the pack leaflet and follow the instructions it gives. You should take the right dose, not more or less. And never stop taking a cancer drug without talking to your specialist first.

     

    You usually carry on taking cabozantinib for as long as it is working, or until the side effects get too bad.

     

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    Small Molecule Inhibitors Cabozantinib (XL184) anti cancer drugs CAS 849217-68-1

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    We are 100% confident of my shipment method, None of our previous packages has ever had any delivery issues.

     

    Chi tiết liên lạc
    Shenzhen Sendi Biotechnology Co.Ltd.

    Người liên hệ: Demi

    Tel: +8618123940985

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